1211909-68-0Relevant academic research and scientific papers
One-pot three component α-aminoalkylation of conjugated nitroalkenes and nitrodienes
Rajesh, Kunjanpillai,Shanbhag, Pramod,Raghavendra, Manjoji,Bhardwaj, Pallavi,Namboothiri, Irishi N.N.
, p. 846 - 849 (2010)
Nitroethylenes possessing aryl, heteroaryl, and alkyl substituents at the β-position as well as δ-substituted nitrobutadienes undergo facile aminoalkylation at the α-position upon treatment with formaldehyde and a secondary amine in the presence of imidazole and trifluoroacetic acid to afford α-aminoalkylated nitroalkenes and nitrodienes in good to excellent yield and stereoselectivity.
