1212-45-9Relevant academic research and scientific papers
Transformations of 1-phenethyl-1,2,3,6-tetrahydropyridines in the presence of trifluoromethanesulfonic acid
Shadrikova, Vera A.,Popov, Alexander S.,Termelyova, Maria V.,Baimuratov, Marat R.,Klimochkin, Yuri N.
, p. 909 - 914 (2020)
[Figure not available: see fulltext.] 1-Phenethyl-1,2,3,6-tetrahydropyridines undergo intramolecular Friedel–Crafts reaction in trifluoromethanesulfonic acid medium, resulting in the formation of azatricyclic structures. It was shown that the direction of
A Short synthesis of benzomorphane analgesics (±)-Metazocine and (±)-Phenazocine
Singh, Kamal Nain,Singh, Pushpinder,Sharma, Arvind Kumar,Singh, Paramjit,Kessar, Satinder V.
experimental part, p. 3716 - 3720 (2010/12/29)
A three step synthesis of (±)-metazocine and (±)-phenazocine starting with 3,4-lutidine is described. The key step involves Lewis acid promoted lithiation/electrophilic substitution reaction of N-alkyl-3,4-dimethyl- 1,2,5,6- tetrahydropyridine. Copyright
