121219-22-5

Basic information

• Product Name: 2,3-Difluoro-4-(octyloxy)-benzeneboronic acid
• Synonyms: 2,3-Difluoro-4-(octyloxy)-benzeneboronic acid
• CAS NO: 121219-22-5
• Molecular Formula: C₁₄H₂₁BF₂O₃
• Molecular Weight: 0
• Mol File: 121219-22-5.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3-Difluoro-4-(octyloxy)-benzeneboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Difluoro-4-(octyloxy)-benzeneboronic acid(121219-22-5)
• EPA Substance Registry System: 2,3-Difluoro-4-(octyloxy)-benzeneboronic acid(121219-22-5)

Safety Data

• Hazardous Substances Data: 121219-22-5(Hazardous Substances Data)

Usage

General Description

2,3-Difluoro-4-(octyloxy)-benzeneboronic acid is a chemical compound used in organic synthesis and drug design. It is a boronic acid derivative with two fluorine atoms attached to the benzene ring and an octyloxy group attached at the para position. Boronic acids are important reagents in Suzuki-Miyaura cross-coupling reactions, a widely used method for the formation of carbon-carbon bonds in organic molecules. This particular compound's unique structure makes it useful for the development of novel pharmaceuticals and agrochemicals. Additionally, its boronic acid functionality allows for the selective and sensitive detection of certain biomolecules, making it a valuable tool in chemical biology and bioanalytical chemistry.

Upstream product

• 111-83-1 1-bromo-octane 
• 6418-38-8 2,3-difluorophenol 
• 121219-21-4 2,3-difluoro-1-n-octyloxybenzene 
• 367-11-3 ortho-difluorobenzene 
• 121219-16-7 (2,3-difluorophenyl)boronic acid 
• 121-43-7 Trimethyl borate 
• 5419-55-6 Triisopropyl borate 

Downstream Products

• 126334-47-2 4'-bromo-2,3-difluoro-4-octyloxybiphenyl 
• 123598-51-6 3-fluoro-4-octyloxyphenylboronic acid 
• 167018-88-4 2-(2',3'-difluoro-4'-octyloxyphenyl)-5-bromopyrimidine 
• 604786-13-2 3-[2,3-difluoro-4-(n-octyloxy)phenyl]-2-fluoro-6-iodopyrazine 
• 604786-10-9 3-(2,3-fluoro-4-(n-octyloxy)phenyl)-2-fluoropyrazine 

Relevant articles and documents

Non-symmetric dimers comprising chalcone and cholesterol entities: An investigation on structure-property correlations

Four series of new dimers formed by interlinking chalcone and cholesterol mesogenic entities through spacers of varying length and parity have been synthesized and characterized by polarizing optical microscopy, differential scanning calorimetry, X-ray diffraction and electrical switching studies. The structure of the chalcone core has been systematically modified to investigate the effect of the molecular structure on the thermal behaviour of the dimers. The study demonstrates the dramatic dependence of thermal behaviour of these dimers on the nature of the chalcone as well as the length and parity of the spacer. the Partner Organisations 2014.

The synthesis and electro-optic properties of liquid crystalline 2- (2,3-difluorobiphenyl-4'-yl)-1,3-dioxanes

Fifty-six novel alkyl and/or alkoxy disubstituted 2-(2,3- difluorobiphenyl-4'-yl)-1,3-dioxanes (DFBPD) were prepared. Smectic C and nematic mesophases were exhibited by most of the alkyl-alkoxy homologues. Conversely, most of the dialkyl compounds exhibited smectic C, smectic A and nematic phases. The birefringence (Δn), dielectric anisotropy (Δε), spontaneous polarisation and response times of two ferroelectric mixtures formulated from the dioxanyl systems were determined. The birefringence results were compared with eight other groups of mixtures where the materials were based on different core systems. The overall electro-optic properties of the DFBPDs were found to be comparable to the best of the eight most commonly used materials in ferroelectric display devices.

Dioxane derivatives

Dioxane derivatives for use as components in liquid crystal devices (LCDs) of general formula (A), wherein X is CH or B; R1, R2 are each A1, OA1, OCOA2, or COOA2 ; A1 is a straight or branched chain alkyl group containing from 1 to 20 carbon atoms and may be substituted with one or more F or CN. A2 is a straight or branched chain alkyl group containing from 1 to 20 carbon atoms and may be substituted with one or more F or CN and if straight may be unsubstituted. Y1, Y2, Y3 may each be (CH2)p, (CH2)p COO or OCO(CH2)p ; p is from 0 to 10, n is 0 or 1, m is 0 or 1, either or both of Z1 and Z2 are F and, when not F, are H; Y4 is a covalent bond or, when n is 0, may be (a) LCDs, containing the devices exhibit very fast switching speed, bi-stable characteristics, enhanced greyscale and storage capabilities and a wide viewing angle.