121245-09-8

Basic information

• Product Name: prosolanapyrone III
• CAS NO: 121245-09-8
• Molecular Weight: 302.37
• Mol File: 121245-09-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: prosolanapyrone III(CAS DataBase Reference)
• NIST Chemistry Reference: prosolanapyrone III(121245-09-8)
• EPA Substance Registry System: prosolanapyrone III(121245-09-8)

Safety Data

• Hazardous Substances Data: 121245-09-8(Hazardous Substances Data)

Upstream product

• 154584-31-3 prosolanapyrone II 

Downstream Products

• 88899-61-0 solanopyrone A 
• 88899-61-0 (-)-solanapyrone A 

Relevant articles and documents

Total synthesis of (-)-solanapyrone A via enzymatic Diels-Alder reaction of prosolanapyrone

The syntheses of prosolanapyrones I (6) and II (7) via the aldol reactions of pyrone and dienal segments have been achieved in five steps in 31% overall yield for 6 and seven steps in 5% overall yield for 7. An improved synthetic route starting from vinylpyrone 27 provided 7 in 11 steps in 12% overall yield. The enzymatic Diels-Alder reaction of 7 affords (-)- solanapyrone A (1) with high enantioselectivity and with good exo- selectivity, which is difficult to attain by chemical methods. In addition, a crude enzyme preparation from Alternaria solani has been used to perform a kinetic resolution of (±)-3.