121246-92-2Relevant academic research and scientific papers
A New Route to 2,3-Disubstituted Pyrazines; Regioselective Metalation of Chloropyrazine
Turck, A.,Mojovic, L.,Queguiner, G.
, p. 881 - 884 (2007/10/02)
Chloropyrazine is regioselectively metalated by lithium amides in tetrahydrofuran to give 3-chloro-2-lithiopyrazine.The reaction of this lithio derivative with electrophiles can either be performed in situ (with the electrophile, e.g., chlorotrimethylsila
