121251-86-3

Basic information

• Product Name: (-)-N-<(2S)-7-hydroxy-1,2,3,4-tetrahydronaphth-2-yl>-(S)-3-chloromandelamide
• CAS NO: 121251-86-3
• Molecular Weight: 331.799
• Mol File: 121251-86-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (-)-N-<(2S)-7-hydroxy-1,2,3,4-tetrahydronaphth-2-yl>-(S)-3-chloromandelamide(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-N-<(2S)-7-hydroxy-1,2,3,4-tetrahydronaphth-2-yl>-(S)-3-chloromandelamide(121251-86-3)
• EPA Substance Registry System: (-)-N-<(2S)-7-hydroxy-1,2,3,4-tetrahydronaphth-2-yl>-(S)-3-chloromandelamide(121251-86-3)

Safety Data

• Hazardous Substances Data: 121251-86-3(Hazardous Substances Data)

Upstream product

• 121216-42-0 (2S)-7-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine 
• 4003-89-8 2-amino-7-methoxy-1,2,3,4-tetrahydronaphthalene 
• 16273-37-3 (S)-2-(3-chlorophenyl)-2-hydroxyacetic acid 
• 85951-60-6 (-)-7-OH-AT 

Downstream Products

• 121489-30-3 [(S)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl]-((S)-7-hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-carbamic acid tert-butyl ester 
• 742664-85-3 N-<(2S)-7-hydroxy-1,2,3,4-tetrahydronaphth-2-yl>-(2S)-2-(3-chlorphenyl)-2-hydroxyethanamine 

Relevant articles and documents

Synthesis and β-adrenergic activity of atypical β-adrenergic phenylethanolaminotetralin stereoisomers

A series of substituted phenylethanolaminotetralins were synthesized as pure stereoisomers and their ability to stimulate atypical β-adrenoceptors selectively was evaluated.The compounds in vitro relative potencies were assessed using the atypical β respo

Process for the O-alkylation of N-(hydroxy)aralkylphenylethanolamines

A process for the preparation of a compound of formula STR1 wherein X represents hydrogen, halogen, trifluoromethyl or lower alkyl group; W represents methyl, Q represents hydrogen or W and Q, together, form an ethylene group and R' represents a lower alkyl group which comprises protecting the amino group of the phenol corresponding to the compound of formula I, submitting the compound thus obtained to an alkylation (with a compound of formula Hal--CH2 --COOR', wherein R' is as defined hereinabove for the formula I and Hal is chlorine, bromine or iodine) and then releasing the amino group of the product thus obtained.