1212838-97-5Relevant articles and documents
Further enantioselective syntheses of α-arylalkanamines via intermediate addition of Grignard reagents to a chiral hydrazone derived from (R)-(-)-2-aminobutan-1-ol
Bataille, Patricia,Paterne, Michel,Brown, Eric
, p. 1579 - 1588 (2007/10/03)
Reaction of various aromatic aldehydes with the chiral hydrazine (R)-(- )-2, derived from 2-aminobutan-1-ol (R)-(-)-1, gave the corresponding hydrazones 5-12. Enantioselective addition of EtMgBr or n-BuMgBr to 5-8 gave the trisubstituted hydrazines 13a-f