121289-75-6Relevant academic research and scientific papers
Differential Effects of a Series of Hydroxamic Acid Derivatives on 5-Lipoxygenase and Cyclooxygenase from Neutrophils and 12-Lipoxygenase from Platelets and Their in Vivo Effects on Inflammation and Anaphylaxis
Huang, Fu-Chih,Shoupe, T. Scott,Lin, Clara J.,Lee, Thomas D. Y.,Chan, Wan-Kit,et al.
, p. 1836 - 1842 (2007/10/02)
The synthesis of a series of novel substituted hydroxamates has been described along with their profile of inhibitory activity against 5-lipoxygenase, 12-lipoxygenase, and cyclooxygenase enzymes.The structure-activity relationship suggests that future mol
