121307-79-7 Usage
General Description
4-(Trifluoromethyl)pyridine-2-thiol is a chemical compound with the molecular formula C6H4F3NS. It is a pyridine derivative containing a trifluoromethyl group and a thiol group attached to the second position of the pyridine ring. 4-(Trifluoromethyl)pyridine-2-thiol is used in organic synthesis and pharmaceutical research as a building block for the synthesis of various bioactive molecules and pharmaceuticals. It can also serve as a ligand in coordination chemistry and catalysis. 4-(Trifluoromethyl)pyridine-2-thiol is known for its strong and distinct odor and should be handled with care due to its potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 121307-79-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,3,0 and 7 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 121307-79:
(8*1)+(7*2)+(6*1)+(5*3)+(4*0)+(3*7)+(2*7)+(1*9)=87
87 % 10 = 7
So 121307-79-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H4F3NS/c7-6(8,9)4-1-2-10-5(11)3-4/h1-3H,(H,10,11)
121307-79-7Relevant articles and documents
Nucleophilic displacement in 2-chloro(trifluoromethyl)pyridines with amines and ammonia
Dunn
, p. 153 - 157 (2007/10/03)
The activating effect of trifluoromethyl groups in 2-chloro(trifluoromethyl)pyridines was investigated by comparing reactions of these compounds and of 2-chloropyridine with secondary cyclic amines. The ammonolysis of 2-chloro-3-trifluoromethylpyridine and 2-chloro-4-trifluoromethylpyridine is also reported and shown to proceed, in contrast to the reported behaviour of 2-chloro-5-trifluoromethylpyridine, without hydrolysis of the trifluoromethyl function. Both 2-amino-3-trifluoromethylpyridine and 2-amino-4-trifluoromethylpyridine were converted (via the corresponding pyridones) to 3-trifluoromethylpyridin-2(1H)-thione and 4-trifluoromethylpyridin-2(1H)-thione, and a number of S-alkyl derivatives of the latter compounds were prepared.
