121307-84-4Relevant academic research and scientific papers
Regio- and Stereoselective Synthesis of Functionalized Vinyl Sulfides Based on Pyridine-2-thiol and Propynoic Acid and Its Derivatives
Potapov,Ishigeev,Musalov,Zinchenko,Chuvashev, Yu. A.,Borodina,Amosova
, p. 1798 - 1802 (2018)
Regio- and stereoselective methods of synthesis of 3-(pyridin-2-ylsulfanyl)prop-2-enoic acid and alkyl (Z)-3-(pyridin-2-ylsulfanyl)prop-2-enoates have been developed on the basis of nucleophilic addition of pyridine-2-thiol to propynoic acid and alkyl propynoates. Reactions of alkyl (Z)-3-(pyridin-2-ylsulfanyl)prop-2- enoates with methyl iodide afforded 2-[(3-alkoxy-3-oxoprop-1-enyl)sulfanyl]-1-methylpyridinium iodides.
Microwave-promoted regio- and stereoselective vinylation of heterocyclic thiols
Rajesh, Nimmakuri,Sarma, Rupam,Prajapati, Dipak
, p. 7834 - 7837 (2014/02/14)
The first stereoselective vinylation of heterocyclic thiols has been reported. Heterocyclic thiols are shown to react efficiently with activated terminal alkynes in an anti-Markovnikov fashion in absence of any catalyst or additive under microwave irradia
