1213091-61-2 Usage
Uses
Used in Organic Synthesis:
(1R)-1-[4-(TERT-BUTYL)PHENYL]PROPYLAMINE is used as a chiral building block for the synthesis of complex organic molecules. Its unique structure allows it to be a key component in creating enantiomerically pure compounds, which are essential in various chemical reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, (1R)-1-[4-(TERT-BUTYL)PHENYL]PROPYLAMINE serves as a precursor for the synthesis of various drugs. Its chiral nature is particularly valuable in developing single-enantiomer medications, which can have superior efficacy and fewer side effects compared to their racemic counterparts.
Used in Agrochemical Industry:
(1R)-1-[4-(TERT-BUTYL)PHENYL]PROPYLAMINE is also utilized as a starting material for the production of agrochemicals, such as pesticides and herbicides. Its ability to create chiral molecules contributes to the development of more effective and targeted agricultural products.
Used in Polymer Production:
(1R)-1-[4-(TERT-BUTYL)PHENYL]PROPYLAMINE is employed in the creation of specific types of polymers, where its chiral properties can influence the polymer's structure and performance. This can lead to the development of new materials with unique characteristics for various applications.
Used as a Reagent in Chemical and Biochemical Research:
(1R)-1-[4-(TERT-BUTYL)PHENYL]PROPYLAMINE is used as a reagent in various research applications, including the study of enzyme mechanisms, the development of new synthetic methods, and the investigation of chiral interactions in chemical and biochemical processes.
Safety Note:
It is important to handle (1R)-1-[4-(TERT-BUTYL)PHENYL]PROPYLAMINE with care, as it is considered a hazardous chemical. Potential health and environmental risks are associated with its use, and proper safety measures should be implemented during its handling and disposal.
Check Digit Verification of cas no
The CAS Registry Mumber 1213091-61-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,3,0,9 and 1 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1213091-61:
(9*1)+(8*2)+(7*1)+(6*3)+(5*0)+(4*9)+(3*1)+(2*6)+(1*1)=102
102 % 10 = 2
So 1213091-61-2 is a valid CAS Registry Number.
1213091-61-2Relevant academic research and scientific papers
Chain branching approach in structure modification of TRPV1 receptor antagonist MK056 and its analogs
Jang, Mijung,Ryu, Chong Hyun,Park, Young-Ho,Kim, Hee-Doo
experimental part, p. 321 - 326 (2012/08/29)
A series of chain branched 1,3-dibenzylthiourea derivatives were designed, synthesized, and evaluated for their antagonist activity against TRPV1. The synthesized chain branched 1,3dibenzylthioureas 9a-g were tested for their antagonist activities against TRPV1 by 45 Ca 2+ influx assay using neonatal rat cultured spinal sensory neurons. Fluorinated ethyl-branched analog 9g showed the most potent antagonist activity with an IC50 value of 0.41 μM, but all of the chain branched analogs were less potent than the parent compounds MK-056 and SC0030, indicating that chain branching on the benzylic position of B-ring is detrimental to potency. Optimized receptor binding seems to be interfered by chain branching, and resulted in decrease in potency.
