121313-15-3 Usage
General Description
"(S)-4-BROMO-HOMO-IBOTENIC ACID" is a chemical compound that belongs to the family of ibotenic acid derivatives. It is a potent agonist of the glutamate receptor, specifically the group I metabotropic glutamate receptors (mGluRs), which are involved in the regulation of synaptic transmission and plasticity in the central nervous system. (S)-4-BROMO-HOMO-IBOTENIC ACID has been studied for its potential pharmaceutical applications, particularly in the areas of neurological and psychiatric disorders. Its structure and function make it a valuable tool in understanding the molecular mechanisms of glutamate receptor activation and its potential therapeutic implications.
Check Digit Verification of cas no
The CAS Registry Mumber 121313-15-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,3,1 and 3 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 121313-15:
(8*1)+(7*2)+(6*1)+(5*3)+(4*1)+(3*3)+(2*1)+(1*5)=63
63 % 10 = 3
So 121313-15-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H5BrN2O4/c6-1-3(2(7)5(10)11)12-8-4(1)9/h2H,7H2,(H,8,9)(H,10,11)/t2-/m0/s1
121313-15-3Relevant articles and documents
An efficient and general enantioselective synthesis of some isoxazole- containing analogues of the neuroexcitant glutamic acid
Pajouhesh, Hassan,Curry, Kenneth
, p. 2757 - 2760 (2007/10/03)
Isoxazole amino acids are an important class of neuroexcitant which are difficult to prepare in enantiopure form. Diastereoselective alkylation of the enantiomerically pure glycine derivative, tert-butoxycarbonyl-2-(tert- butyl)-3-methyl-4-oxo-1-imidazolidinecarboxylate (Boc-BMI) with 4- bromomethyl-2-methoxymethyl-5-methylisoxazolin-5-one 5 or 5-bromomethyl-4- bromo-3-methoxyisoxazole, gives intermediates which under mild hydrolysis conditions produce the amino acids (S)- and (R)-bromohomoibotenic acid and (S)- and (R)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl) propionic acid with e.e. >99%.
