1213162-90-3 Usage
Uses
Used in Pharmaceutical Industry:
(1R)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE is used as a building block for the creation of new drugs. Its chiral nature allows for the development of enantiomerically pure compounds, which can exhibit different biological activities and reduce potential side effects. (1R)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE is particularly useful in the synthesis of chiral pharmaceuticals, where the stereochemistry of the molecule can significantly impact its efficacy and safety.
Used in Agrochemical Industry:
(1R)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE is used in the synthesis of agrochemicals, such as pesticides and herbicides. Its chiral properties enable the development of more effective and selective agrochemicals, reducing the environmental impact and improving crop protection.
Used in Chiral Ligand Production:
(1R)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE is used in the production of chiral ligands for catalysis. These ligands are essential in asymmetric synthesis, allowing for the selective formation of enantiomerically pure compounds. The use of chiral ligands can improve the efficiency and selectivity of catalytic reactions, leading to the production of high-quality chemical products.
Used in Organic Chemistry Research:
(1R)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE is an important tool in the field of organic chemistry, particularly in the development of asymmetrical synthesis methods. Its unique structure and properties make it a valuable compound for studying and understanding the mechanisms of enantioselective reactions. This knowledge can be applied to the design and synthesis of new chiral compounds with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 1213162-90-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,3,1,6 and 2 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1213162-90:
(9*1)+(8*2)+(7*1)+(6*3)+(5*1)+(4*6)+(3*2)+(2*9)+(1*0)=103
103 % 10 = 3
So 1213162-90-3 is a valid CAS Registry Number.
1213162-90-3Relevant academic research and scientific papers
Enantiodivergent approach to trifluoromethylated amines: A concise route to both enantiomeric analogues of calcimimetic NPS R-568
Fernandez, Inmaculada,Valdivia, Victoria,Alcudia, Ana,Chelouan, Ahmed,Khiar, Noureddine
experimental part, p. 1502 - 1509 (2010/06/15)
Reported herein is a straightforward and enantiodivergent synthesis of both enantiomers of trifluoromethylated analogues of calcimimetic NPS R-569 in a highly estereoselective manner. The synthesis features a diastereoselective synthesis of the N-(isopropylsulfinyl)imine unit by the "DAG methodology" and a diastereoselective addition of Ruppert Prakash's reagent to the imine as the key steps. No protecting groups were necessary, permitting an atom economic synthesis in only six steps. Further addition reactions of the CF3 anion to different N-(isopropylsulfinyl)imines were performed to demonstrate the suitability of the sulfinyl substituent to balance perfectly reactivity and diastereoselectivity.
