1213263-15-0

Basic information

• Product Name: C₁₃H₁₃F₆N₃S
• Synonyms: C₁₃H₁₃F₆N₃S
• CAS NO: 1213263-15-0
• Molecular Weight: 357.323
• Mol File: 1213263-15-0.mol

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₃F₆N₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₃F₆N₃S(1213263-15-0)
• EPA Substance Registry System: C₁₃H₁₃F₆N₃S(1213263-15-0)

Safety Data

• Hazardous Substances Data: 1213263-15-0(Hazardous Substances Data)

Upstream product

• 1213263-28-5 C₁₈H₂₁F₆N₃O₂S 

Relevant articles and documents

4-Aminothiourea prolinol tert-butyldiphenylsilyl ether: A chiral secondary amine-thiourea as organocatalyst for enantioselective anti-mannich reactions

anti-Selective Mannich reactions of N-p-methoxyphenyl (PMP)-protected α-iminoglyoxylate with unmodified aldehydes or ketones were effectively catalyzed by 4-aminothiourea prolinol tert-butyldiphenylsilyl ether. The reactions led to chiral β-amino carbonyl compounds in high yields (up to 94%), excellent diastereo- and enantioselectivities (up to 98% de and >99% ee). The study demonstrated for the first time that direct Mannich-type reactions of unmodified aldehydes or ketones to aiminoglyoxylate can be promoted by secondary amine-thiourea chiral organocatalyst.