1213269-98-7 Usage
General Description
EPI 743, also known as alpha-lipoic acid ester, is a novel small molecule drug that has shown potential in treating mitochondrial diseases and neurodegenerative disorders. It works by targeting and protecting mitochondria, which are the energy production centers of cells, from oxidative stress and damage. EPI 743 has been found to improve mitochondrial function and reduce oxidative damage, leading to potential benefits in conditions such as Leigh syndrome, Friedreich's ataxia, and other genetic and acquired mitochondrial diseases. Research on EPI 743 is ongoing, but early studies have shown promising results, making it a potential therapeutic option for a range of mitochondrial and neurodegenerative disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 1213269-98-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,3,2,6 and 9 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1213269-98:
(9*1)+(8*2)+(7*1)+(6*3)+(5*2)+(4*6)+(3*9)+(2*9)+(1*8)=137
137 % 10 = 7
So 1213269-98-7 is a valid CAS Registry Number.
1213269-98-7Relevant articles and documents
α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging
Shrader, William D.,Amagata, Akiko,Barnes, Adam,Enns, Gregory M.,Hinman, Andrew,Jankowski, Orion,Kheifets, Viktoria,Komatsuzaki, Ryo,Lee, Edgar,Mollard, Paul,Murase, Katsuyuki,Sadun, Alfredo A.,Thoolen, Martin,Wesson, Kieron,Miller, Guy
scheme or table, p. 3693 - 3698 (2011/08/06)
We report that α-tocotrienol quinone (ATQ3) is a metabolite of α-tocotrienol, and that ATQ3 is a potent cellular protectant against oxidative stress and aging. ATQ3 is orally bioavailable, crosses the blood-brain barrier, and has demonstrated clinical res