121328-31-2Relevant academic research and scientific papers
Acyclic Stereoselection in the Alkylation of Chiral Dipole-Stabilized Organolithiums: A Self-Immolative Chirality Transfer Process for the Synthesis of Primary Amines
Gawley, Robert E.,Rein, Kathleen,Chemburkar, Sanjay
, p. 3002 - 3004 (2007/10/02)
A comparison of 1,3- and 1,5-asymmetric induction shows the former to have far greater selectivity in the methylation of chiral dipole-stabilized organolithiums.The asymmetric alkylation of N-benzyloxazolidinones is employed as the key step in a new synthesis of primary amines by asymmetric alkylation α to nitrogen.
