121329-77-9Relevant academic research and scientific papers
Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer's agents: Structure-activity relationship study of Arg-mimetic region
Ngo, Van T.H.,Hoang, Van-Hai,Tran, Phuong-Thao,Ann, Jihyae,Cui, Minghua,Park, Gyungseo,Choi, Sun,Lee, Jiyoun,Kim, Hee,Ha, Hee-Jin,Choi, Kwanghyun,Kim, Young-Ho,Lee, Jeewoo
supporting information, p. 1035 - 1049 (2018/02/12)
Pyroglutamate-modified amyloid β peptides (pGlu-Aβ) are highly neurotoxic and promote the formation of amyloid plaques. The pGlu-Aβ peptides are generated by glutaminyl cyclase (QC), and recent clinical studies indicate that QC represents an alternative t
Synthesis and Biological Activity of Photoactive Derivatives of Erythromycin
Arevalo, M. Angeles,Tejedor, Francisco,Polo, Florentino,Ballesta, J. P. G.
, p. 2200 - 2204 (2007/10/02)
Five photoactive derivatives of erythromycin have been synthesized by linking to 9(S)-aminoerythromycin either an aryl azide or a p-nitrophenyl ether.One derivative is an amide formed by reaction with (5-azido-2-formyl-phenoxy)acetic acid.Three derivative
