121336-29-6

Basic information

• Product Name: (3aR,5R,6R,6aR)-5-Ethyl-6-(4-methoxy-benzyloxy)-2,2,6-trimethyl-tetrahydro-furo[2,3-d][1,3]dioxole
• Synonyms: (3aR,5R,6R,6aR)-5-Ethyl-6-(4-methoxy-benzyloxy)-2,2,6-trimethyl-tetrahydro-furo[2,3-d][1,3]dioxole
• CAS NO: 121336-29-6
• Molecular Weight: 322.401
• Mol File: 121336-29-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3aR,5R,6R,6aR)-5-Ethyl-6-(4-methoxy-benzyloxy)-2,2,6-trimethyl-tetrahydro-furo[2,3-d][1,3]dioxole(CAS DataBase Reference)
• NIST Chemistry Reference: (3aR,5R,6R,6aR)-5-Ethyl-6-(4-methoxy-benzyloxy)-2,2,6-trimethyl-tetrahydro-furo[2,3-d][1,3]dioxole(121336-29-6)
• EPA Substance Registry System: (3aR,5R,6R,6aR)-5-Ethyl-6-(4-methoxy-benzyloxy)-2,2,6-trimethyl-tetrahydro-furo[2,3-d][1,3]dioxole(121336-29-6)

Safety Data

• Hazardous Substances Data: 121336-29-6(Hazardous Substances Data)

Upstream product

• 105-13-5 4-Methoxybenzyl alcohol 
• 64638-66-0 (3aR,5R,6R,6aR)-5-Ethyl-2,2,6-trimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-ol 
• 212051-17-7 4-methoxybenzyl 2,2,2-trifluoroacetimidate 

Relevant articles and documents

Activated dimethyl sulfoxide dehydration of amide and its application to one-pot preparation of benzyl-type perfluoroimidates

Various types of primary amides were treated under an activated dimethyl sulfoxide (DMSO) species, (COCl)2-DMSO and Et3N, as a dehydrating agent to obtain nitriles in excellent yield. This dehydration system was extended to a one-pot preparation of perfluoroimidates via volatile perfluoronitriles from perfluoroamides. Fifteen benzyl-type perfluoroimidates can be prepared in 70-90% yield as more stable imidates than the trichloro analogue. MPM- and DMPM-perfluoroimidates can be used to protect alcohols in place of the trichloroacetimidate with excellent chemical properties and in comparable yields.