121345-17-3

Basic information

• Product Name: 3-Cyclohexylamino-5-methyl-[1,4]thiazin-2-one
• CAS NO: 121345-17-3
• Molecular Weight: 224.327
• Mol File: 121345-17-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Cyclohexylamino-5-methyl-[1,4]thiazin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyclohexylamino-5-methyl-[1,4]thiazin-2-one(121345-17-3)
• EPA Substance Registry System: 3-Cyclohexylamino-5-methyl-[1,4]thiazin-2-one(121345-17-3)

Safety Data

• Hazardous Substances Data: 121345-17-3(Hazardous Substances Data)

Upstream product

• 108-91-8 cyclohexylamine 
• 121345-25-3 3-chloro-5-methyl-2-oxo-2H-1,4-thiazine 
• 106853-26-3 2,2-dimethoxy-5-methyl-2H-1,4-thiazin-3(4H)-one 
• 121345-24-2 5-methyl-2,3-dioxo-2H,4H-1,4-thiazine 
• 22390-69-8 5-methyl-2H-1,4-thiazin-3(4H)-one 

Relevant articles and documents

Synthesis of 3-substituted 2-oxo-1,4-thiazines and evaluation of their protective effect against endotoxin shock in mouse

5-Methyl-2,3-dioxo-2H,4H-1,4-thiazine (7) was obtained by the oxidation of 5-methyl-2H-1,4-thiazin-3(4H)-one (5) with m-chloroperbenzoic acid in MeOH, followed by acid hydrolysis of the resulting 2,2-dimethoxy-1,4-thiazine (6). 3-Chloro-2-oxo-1,4-thiazine (10), which was obtained from 7 by heating with phosphorous oxychloride, reacted with various nucleophiles to give 3-substituted 2-oxo-1,4-thiazines (11a-y). Some of these 2-oxo-1,4-thiazines, 11a-b, e, o and r-s, showed a protective effect against endotoxin shock in D-galactosamine-sensitized mice.