1213509-59-1 Usage
General Description
(2R)-2-(3,5-dimethylphenyl)pyrrolidine is a chemical compound with the formula C13H19N. It is a pyrrolidine derivative, which is a type of organic compound containing a five-membered ring with a nitrogen atom. The presence of the 3,5-dimethylphenyl group in the molecule gives it some unique chemical and physical properties. (2R)-2-(3,5-dimethylphenyl)pyrrolidine is often used as a chiral building block in the synthesis of pharmaceuticals and other organic compounds due to its asymmetric carbon center. It has also been studied for its potential therapeutic applications, including as a potential treatment for various medical conditions. Overall, (2R)-2-(3,5-dimethylphenyl)pyrrolidine is an important compound in the field of organic chemistry and pharmaceutical development.
Check Digit Verification of cas no
The CAS Registry Mumber 1213509-59-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,3,5,0 and 9 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1213509-59:
(9*1)+(8*2)+(7*1)+(6*3)+(5*5)+(4*0)+(3*9)+(2*5)+(1*9)=121
121 % 10 = 1
So 1213509-59-1 is a valid CAS Registry Number.
1213509-59-1Relevant articles and documents
Zinc-Catalyzed Asymmetric Hydrosilylation of Cyclic Imines: Synthesis of Chiral 2-Aryl-Substituted Pyrrolidines as Pharmaceutical Building Blocks
W?glarz, Izabela,Michalak, Karol,Mlynarski, Jacek
supporting information, p. 1317 - 1321 (2020/12/09)
The first successful enantioselective hydrosilylation of cyclic imines promoted by a chiral zinc complex is reported. In situ generated zinc-ProPhenol complex with silane afforded pharmaceutically relevant enantioenriched 2-aryl-substituted pyrrolidines in high yields and with excellent enantioselectivities (up to 99% ee). The synthetic utility of presented methodology is demonstrated in an efficient synthesis of the corresponding chiral cyclic amines, being pharmaceutical drug precursors to the Aticaprant and Larotrectinib. (Figure presented.).