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(R)-N-(4-(1-aminoethyl)phenyl)-6-(pyridin-4-yl)quinazolin-2-amine is a complex organic compound characterized by a quinazoline core and a phenylethylamine side chain. It functions as a potent and selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase, a key enzyme involved in the regulation of cell growth and division. (R)-N-(4-(1-aminoethyl)phenyl)-6-(pyridin-4-yl)quinazolin-2-amine has demonstrated significant potential in the medical field, particularly for the treatment of various cancers that overexpress EGFR, due to its ability to inhibit EGFR signaling pathways. Its therapeutic applications extend beyond oncology, with potential in treating other diseases such as arthritis and diabetes, making it a subject of ongoing research and development for new treatment options.

1213700-07-2

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1213700-07-2 Usage

Uses

Used in Oncology:
(R)-N-(4-(1-aminoethyl)phenyl)-6-(pyridin-4-yl)quinazolin-2-amine is used as a targeted cancer therapy agent for the treatment of various cancers that overexpress the epidermal growth factor receptor (EGFR). Its mechanism of action involves the inhibition of EGFR tyrosine kinase, which is crucial in controlling cell growth and division, thereby potentially suppressing tumor growth and progression.
Used in Pharmaceutical Research and Development:
In the pharmaceutical industry, (R)-N-(4-(1-aminoethyl)phenyl)-6-(pyridin-4-yl)quinazolin-2-amine is used as a lead compound for the development of new drugs. Its unique ability to inhibit EGFR signaling pathways positions it as a promising candidate for further research into its therapeutic effects and potential applications in treating a range of diseases, including but not limited to cancer.
Used in the Treatment of Arthritis:
(R)-N-(4-(1-aminoethyl)phenyl)-6-(pyridin-4-yl)quinazolin-2-amine is used as a potential therapeutic agent for arthritis. Its role in inhibiting EGFR, which is implicated in inflammatory processes, suggests that it may help manage the symptoms and progression of arthritis, offering a new avenue for treatment.
Used in the Treatment of Diabetes:
In the field of diabetes management, (R)-N-(4-(1-aminoethyl)phenyl)-6-(pyridin-4-yl)quinazolin-2-amine is used as a potential treatment option. Its impact on EGFR signaling, which can influence insulin resistance and glucose metabolism, positions it as a candidate for further exploration in the development of diabetes therapies.
These applications highlight the versatility and potential impact of (R)-N-(4-(1-aminoethyl)phenyl)-6-(pyridin-4-yl)quinazolin-2-amine across different areas of medical science and healthcare.

Check Digit Verification of cas no

The CAS Registry Mumber 1213700-07-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,3,7,0 and 0 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1213700-07:
(9*1)+(8*2)+(7*1)+(6*3)+(5*7)+(4*0)+(3*0)+(2*0)+(1*7)=92
92 % 10 = 2
So 1213700-07-2 is a valid CAS Registry Number.

1213700-07-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-N-(4-(1-aminoethyl)phenyl)-6-(pyridin-4-yl)quinazolin-2-amine

1.2 Other means of identification

Product number -
Other names (R)-N-(4-(1-AMINOETHYL)PHENYL)-6-(PYRIDIN-4-YL)QUINAZOLIN-2-AMINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1213700-07-2 SDS

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