1213702-80-7Relevant articles and documents
Design, synthesis, and evaluation of 2-methyl- and 2-amino-N-aryl-4,5- dihydrothiazolo[4,5-h]quinazolin-8-amines as ring-constrained 2-anilino-4-(thiazol-5-yl)pyrimidine cyclin-dependent kinase inhibitors
McIntyre, Neil A.,McInnes, Campbell,Griffiths, Gary,Barnett, Anna L.,Kontopidis, George,Slawin, Alexandra M. Z.,Jackson, Wayne,Thomas, Mark,Zheleva, Daniella I.,Wang, Shudong,Blake, David G.,Westwood, Nicholas J.,Fischer, Peter M.
supporting information; experimental part, p. 2136 - 2145 (2010/08/07)
Following the recent discovery and development of 2-anilino-4-(thiazol-5- yl)pyrimidine cyclin dependent kinase (CDK) inhibitors, a program was initiated to evaluate related ring-constrained analogues, specifically, 2-methyl- and 2-amino-N-aryl-4,5-dihydr