121378-07-2Relevant academic research and scientific papers
Enanthioselective Phase-Transfer Catalysis by Optically Active Crown Ethers
Dehmlow, Eckehard V.,Sauerbier, Christiane
, p. 181 - 186 (2007/10/02)
1,2-Bis(hydroxymethyl)-15-crown-5 (1a), its dibenzyl ether (1b), and a series of esters with substituted benzoic acid (3) were probed as enanthioselective phase-transfer catalysts.Optical yields were observed in epoxidations of unsaturated ketones by hypochlorite and in cyanide additions to such compounds.The maximum ee value was 45percent.Polar side groups of the optically active crown ethers proved to be vital for enanthiomeric excesses.
