121385-69-1

Basic information

• Product Name: 5-HYDRAZINO-ISOPHTHALIC ACID
• Synonyms: 5-HYDRAZINO-ISOPHTHALIC ACID;PHENYLHYDRAZIN-3,5-DICARBOXYLIC ACID;VITAS-BB TBB000155;1,3-Benzenedicarboxylicacid,5-hydrazino-;1,3-Benzenedicarboxylicacid,5-hydrazino-(9CI)
• CAS NO: 121385-69-1
• Molecular Formula: C₈H₈N₂O₄
• Molecular Weight: 196.16
• Product Categories: HYDRAZINE;AMINOACID
• Mol File: 121385-69-1.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-HYDRAZINO-ISOPHTHALIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-HYDRAZINO-ISOPHTHALIC ACID(121385-69-1)
• EPA Substance Registry System: 5-HYDRAZINO-ISOPHTHALIC ACID(121385-69-1)

Safety Data

• Hazardous Substances Data: 121385-69-1(Hazardous Substances Data)

Usage

Functional Group

Contains a hydrazine functional group

Applications

1. Corrosion inhibitor
2. Catalyst
3. Building block for organic compound synthesis
4. Potential use in pharmaceuticals
5. Fluorescent probe for biological imaging and sensing applications

Upstream product

• 99-31-0 5-aminoisophthalic acid 

Downstream Products

• 51304-73-5 dimethyl 5-hydrazinylisophthalate 
• 873773-67-2 C₁₂H₈N₄O₄ 
• 226936-47-6 7,16-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane 
• 226936-45-4 7,13-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10-trioxa-7,13-diazacyclopentadecane 

Relevant articles and documents

Modeling molecular interactions of propounded pyrazole based drug candidates against bacterial DNA gyrase: Validation by syntheses and biological studies

A class of nitrogen-based heterocycles, pyrazoles and their derivatives, are cardinal agents in the field of pharmacology. Here, we have conducted in silico studies on newly designed pyrazole based drug molecules, thereby revealing their activities and in

Fluorogenic naked-eye sensing and live-cell imaging of cyanide by a hydrazine-functionalized CAU-10 metal-organic framework

A hydrazine-functionalized, highly stable Al(iii) based metal-organic framework (MOF) with CAU-10 (CAU = Christian-Albrechts-University) framework topology namely CAU-10-N2H3 (1) was specifically designed to detect lethal CN- ions in aqueous medium. The MOF was characterized by X-ray powder diffraction, infrared spectroscopy, gas sorption and thermogravimetric analyses. The isophthalate ligand in CAU-10 was functionalized by the hydrazine group to make the acidic -NH protons easily available to the CN- ions. Indeed, the activated compound (1′) showed highly selective and sensitive responses to CN- ions over other common anions with a detection limit of 0.48 μM. A rapid fluorescence enhancement was observed for 1′ with a large spectral shift (Δλ = 30 nm) in the presence of CN- ions in aqueous solution with the development of visible green fluorescence under a UV lamp. Due to the excellent detection performance to CN- by 1′ in aqueous medium, the material was further used for CN- detection in real water samples. The fluorescence increment with a large blue shift is attributed to the cyanide-induced deprotonation of the -NH group, which was confirmed by 1H NMR titration measurements. The initial photo-induced electron transfer (PET) process is prohibited by this deprotonation, which causes the fluorescence enhancement. Time-resolved fluorescence lifetime measurements suggest that 1′ can also act as a lifetime based CN- sensor. Finally, the CN- sensing ability of 1′ inside living RAW 264.7 macrophages was demonstrated through live-cell imaging investigations.

WATER-SOLUBLE AZO COMPOUND AND SALT THEREOF, INK COMPOSITION AND COLORED BODY

PROBLEM TO BE SOLVED: To provide a water-soluble yellow pigment (compound) having high water solubility and excellent in a variety of fastness such as water proofness, moisture proofness, ozone gas resistance, wear resistance, and light resistance, partic