121392-24-3Relevant academic research and scientific papers
Perfluoro-tagged benzyloxycarbonyl protecting group and its application in fluorous biphasic systems
Schwinn, Dominik,Bannwarth, Willi
, p. 255 - 264 (2002)
The synthesis of a new perfluoro-tagged benzyloxycarbonyl protecting group is reported, as well as its application in the parallel protection of amines. Isolation of the protected amines was performed by simple liquid-liquid extraction between perfluorinated and organic solvents. Deprotection was achieved by standard hydrogenolysis. The novel protecting group was also applied to cyclization protocols leading to quinazoline-2,4-diones. These products were isolated by simple extraction procedures.
