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• 6552-67-6 4'-methoxy-4-nitrochalcone 
• 137-07-5 2-amino-benzenethiol 
• 35031-93-7 1-(4-methoxyphenyl)-3-(4-nitrophenyl)propan-1-one 

Relevant academic research and scientific papers

Efficient and eco-friendly syntheses of 1,5-benzothiazepines and 1,5-benzodiazepines catalyzed by [Hmim][NO3] under mild conditions

This article presents a synthetic method and reaction mechanism of the 1,5-benzothiazepines and 1,5-benzodiazepines derivatives. In this research, 36 thiazepines and diazepines (mostly new) with a new method have been prepared and their structures have been characterized by spectroscopic methods. Crystal structures of a new thiazepine and diazepine (seven-membered rings) have also been determined and compared with thiazine (six-membered ring). In this method, N-methylimidazolium nitrate [Hmim][NO3] has been used as a catalyst that acts as an environmental friendly system.

Syntheses of potentially bioactive [1,2,4]oxadiazolo[5,4-d]benzothiazepines by 1,3-dipolar cycloaddition

The chalcones, 2a-2l reacted with o-aminobenzenthiol to give a series of 1,5-benzothiazepines, 3a-3l. The [3+2] 1, 3-dipolar cycloaddition reactions of 3a-3l with ethyl chlorooximidoacetate in the presence of Et3N afforded the target compounds, 4a-4l possessing an additional 1,2,4-oxadiazole ring fused to the heptaatomic nucleus. The structures have been elucidated by spectral methods and X-ray crystallographic analysis.

Syntheses of 1,5-Benzothiazepines: Part IV-Synthesis of 2,4-Diaryl-2,3-dihydro-1,5-benzothiazepines

2,4-Diaryl-2,3-dihydro-1,5-benzothiazepines (IIa-f) have been prepared in satisfactory yields by the reaction of chalkones (Ia-f) with 2-aminothiophenol in anhyd. toluene and their structures established by elemental analyses and spectral data (IR, PMR and mass).