1214224-23-3Relevant academic research and scientific papers
Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl
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Page/Page column 106, (2010/04/24)
The present invention relates to compounds of formula (I) wherein R1, R2 and R3 are as defined in the description, to their pharmaceutical compositions and use thereof for the treatment of cancer expressing oncogenic ALK protein, particularly anaplastic l
Synthesis of 2-, 3-, and 4-substituted pyrido[2,3-b]indoles by C-N, C-O, and C-C(sp) bond formation
Schneider, Cedric,Goyard, David,Gueyrard, David,Joseph, Benoit,Goekjian, Peter G.
experimental part, p. 6665 - 6677 (2011/02/25)
The synthesis of 2-, 3-, and 4-substituted α-carbolines is described starting from the corresponding chloropyrido[2,3-b]indoles by Buchwald-Hartwig and Sonogashira cross-coupling reactions. Regioselective Sonogashira reactions on 2,4-dichloropyrido[2,3-b]
