1214260-83-9Relevant academic research and scientific papers
A PROCESS FOR THE PREPARATION OF 3-ARYL-2-HYDROXY PROPANOIC ACID COMPOUNDS
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, (2014/12/09)
The present disclosure provides a process for synthesis of 3-aryl-2-hydroxy propanoic acid derivatives of formula (S)-1. wherein R1 represents H or (C1-C5) alkyl groups and R2 represents (C1-C5) alkyl groups.
A new enantioselective synthesis of (S)-2-ethoxy-3-(4-hydroxyphenyl) propanoic acid esters (EEHP and IEHP), useful pharmaceutical intermediates of PPAR agonists
Mujahid,Kunte,Muthukrishnan
supporting information, p. 3223 - 3226 (2014/06/09)
A new enantioselective synthetic route to the title compounds has been developed in a simple and practical way with high enantiopurity using commercially available starting material.
Stereochemical analysis of the enzymic reduction of the double bond of α- and β-substituted nitrostyrenes and α-ethoxycinnamaldehyde through deuterium labelling experiments
Brenna, Elisabetta,Fronza, Giovanni,Fuganti, Claudio,Gatti, Francesco G.
experimental part, p. 5077 - 5084 (2010/10/21)
2H NMR studies and comparison with authentic labelled reference compounds prepared from the (Z)-acetamidocinnamic acid 10 and from (Z)-2-ethoxy-3-(4-methoxyphenyl) prop-2-en-1-ol (14), respectively, by catalytic syn reduction with deuterium gas
New stereospecific synthesis of Tesaglitazar and Navaglitazar precursors
Brenna, Elisabetta,Fuganti, Claudio,Gatti, Francesco G.,Parmeggiani, Fabio
experimental part, p. 2694 - 2698 (2010/04/29)
A new synthetic route of to pharmaceutical intermediates (S)-1a-b and (S)-14 is reported. The reaction pathway is based on the baker's yeast-mediated reduction of the α-alkoxy cinnamaldehydes 9a-c to give the corresponding (S)-alcohols in good yields and
