1214326-89-2 Usage
General Description
4-Amino-3-bromo-5-fluoropyridine is a synthetic chemical compound, specifically an aromatic compound and a member of the pyridine family with an amino group, a bromine atom, and a fluorine atom attached. 4-Amino-3-bromo-5-fluoropyridine has a molecular formula of C5H4BrFN2 and a molecular weight of 191.999g/mol. Its systematic name is 4-amino-3-bromopyridin-5-yl fluoride. Like many other advanced intermediates, 4-Amino-3-bromo-5-fluoropyridine is often used in chemical research, drug discovery, and pharmaceutical industry. For safety, it needs to be handled with care as exposure could cause irritation to the skin, eyes, and respiratory system.
Check Digit Verification of cas no
The CAS Registry Mumber 1214326-89-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,4,3,2 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1214326-89:
(9*1)+(8*2)+(7*1)+(6*4)+(5*3)+(4*2)+(3*6)+(2*8)+(1*9)=122
122 % 10 = 2
So 1214326-89-2 is a valid CAS Registry Number.
1214326-89-2Relevant articles and documents
TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE
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Paragraph 1307; 1308, (2021/02/12)
The present disclosure relates to bifunctional compounds, which find utility as modulators of tan protein. In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a VHL or cereblon ligand which binds to the E3 ubiquitin ligase and on the other end a moiety which binds tan protein, such that tan protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of tan. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of tan protein. Diseases or disorders that result from aggregation or accumulation of tan protein are treated or prevented with compounds and compositions of the present disclosure.
