1214377-42-0

Basic information

• Product Name: 5-bromo-2-methoxy-3-(trifluoromethyl)pyridine
• Synonyms: 5-bromo-2-methoxy-3-(trifluoromethyl)pyridine;5-broMo-3-(trifluoroMethyl)-2-Methoxypyridine;Pyridine, 5-bromo-2-methoxy-3-(trifluoromethyl)-
• CAS NO: 1214377-42-0
• Molecular Formula: C₇H₅BrF₃NO
• Molecular Weight: 256.0199096
• Product Categories: Fluorine series
• Mol File: 1214377-42-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 208 °C at 760 mmHg
• Flash Point: 79.6 °C
• Appearance: /
• Density: 1.637 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -1.38±0.20(Predicted)
• CAS DataBase Reference: 5-bromo-2-methoxy-3-(trifluoromethyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-methoxy-3-(trifluoromethyl)pyridine(1214377-42-0)
• EPA Substance Registry System: 5-bromo-2-methoxy-3-(trifluoromethyl)pyridine(1214377-42-0)

Safety Data

• Hazardous Substances Data: 1214377-42-0(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-methoxy-3-(trifluoromethyl)pyridine is a chemical compound with the formula C7H5BrF3NO. It is a pyridine derivative with a bromo substitution at the 5 position, a methoxy group at the 2 position, and a trifluoromethyl group at the 3 position. 5-Bromo-2-methoxy-3-(trifluoromethyl)pyridine is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is also used as a reagent in organic chemistry reactions, specifically in the formation of carbon-carbon and carbon-heteroatom bonds. 5-Bromo-2-methoxy-3-(trifluoromethyl)pyridine is a valuable intermediate in the production of various functional materials and has a wide range of applications in the chemical industry.

Upstream product

• 65753-47-1 2-chloro-3-trifluoromethyl-pyridine 
• 121643-44-5 2-methoxy-3-(trifluoromethyl)pyridine 

Downstream Products

• 1354690-24-6 1-[(3S)-3-({5,6,7,8-tetrahydro-6-[6-methoxy-5-(trifluoromethyl)pyridin-3-yl]pyrido[4,3-d]pyrimidin-4-yl}amino)pyrrolidin-1-yl]propan-1-one 
• 1354691-99-8 1-{(S)-3-[6-(6-methoxy-5-trifluoromethyl-pyridin-3-yl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-ylamino]-pyrrolidin-1-yl}-propan-1-one hippurate 
• 1150561-61-7 2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridine 
• 1211532-15-8 6-methoxy-5-(trifluoromethyl)nicotinic acid 
• 1354690-31-5 ((S)-3-(6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-ylamino)pyrrolidin-1-yl)((1R,4R)-4-methoxycyclohexyl)methanone 
• 1354690-30-4 ((S)-3-(6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-ylamino)pyrrolidin-1-yl)((1S,4S)-4-methoxycyclohexyl)methanone 

Relevant articles and documents

2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF

To provide a compound useful as an active ingredient of a pharmacological composition for the treatment of urinary storage symptoms, dysuria, lower urinary tract diseases, and the like. [Solution] The inventors perfected the present invention after discov

QUINAZOLINE DERIVATIVES AS PI3K MODULATORS

The invention relates to substituted quinazoline derivative of the formula (I), wherein A, X1, X2, X3, X4 and R5 are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of the PI3K enzymes.

SOLID FORMS AND SALTS OF TETRAHYDRO-PYRIDO-PYRIMIDINE DERIVATIVES

The invention relates to crystalline anhydrous forms, crystalline solvate forms and/or salt forms including crystalline salt forms of {(S)-3-[6-(6-methoxy-5-methyl-pyridin-3-yl)-5,6,7,8- tetrahydro-pyrido[4,3-d]pyrimidin-4-yloxy]-pyrrolidin-1-yl}-(tetrahydro-pyran-4-yl)-methanone or salt forms including crystalline salt forms of 1-{(S)-3-[6-(6-methoxy-5-trifluoromethyl- pyridin-3-yl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-ylamino]-pyrrolidin-1-yl}-propan-1-on; pharmaceutical compositions and combinations including these forms as well as to methods of using these forms, including their pharmaceutical compositions and combinations for the treatment of diseases.