1214737-97-9

Upstream product

• 860264-36-4 (2R,3R,4R,5R)-2-((benzyloxy)methyl)-3,4-bis(benzyloxy)-5-allyl-N-(benzyoxycarbonyl)pyrrolidine 

Downstream Products

• 1214738-01-8 (3R,4aR,5R,6R,7R)-5,6-bis(benzyloxy)-7-(benzyloxy-methyl)-3-(hydroxymethyl)hexahydro-1H-pyrrolo[1,2-c][1,3]oxazin-1-one 

Relevant academic research and scientific papers

Synthesis of d-arabinose-derived polyhydroxylated pyrrolidine, indolizidine and pyrrolizidine alkaloids. Total synthesis of hyacinthacine A2

Several new polyhydroxylated alkaloids including pyrrolidines with a long side chain and 3-(hydroxymethyl) indolizidines were prepared from a common nitrone easily obtained from d-arabinose. In addition, a total synthesis of hyacinthacine A2 has been achieved in five steps and 67.7% overall yield starting from the same d-arabino-derived nitrone. All synthesized compounds have a common structural feature consisting of a pyrrolidine ring with d-arabino configuration.