1214890-79-5Relevant academic research and scientific papers
Metal-free sequential reaction via a propargylation, annulation and isomerization sequence for the one-pot synthesis of 2,3-disubstituted benzofurans
Li, Wen-Tao,Nan, Wen-Hui,Luo, Qun-Li
, p. 34774 - 34779 (2014)
A metal-free one-pot synthesis of 2,3-disubstituted benzofurans is described, which allows for the reactions to be performed under ambient conditions with readily accessible propargyl alcohols and general phenols, including phenols substituted with an ele
Direct Propargylation of ortho-Quinone Methides with Alkynyl Zinc Reagents: An Application to the One-Pot Synthesis of 2,3-Disubstituted Benzofurans
Miao, Maozhong,Ren, Hongjun,Song, Jinyu,Sun, Manman,Wang, Lei,Yin, Wenguang
supporting information, p. 818 - 822 (2020/05/19)
A transition-metal-free propargylation of ortho-quinone methides (o-QMs) with alkynyl zinc reagents was achieved. A conjugate alkynylation of an o-QM and subsequent cyclization sequence in the presence of KO t-Bu for the synthesis of 2,3-disubstituted benzofurans in one pot was developed. This efficient strategy exhibits good functional-group compatibility and gives moderate to good yields. The present reaction might serve as an attractive method for the synthesis of polysubstituted benzofurans.
Amberlite IR-120H as an efficient and versatile solid phase catalyst for nucleophilic substitution of propargylic alcohols
Gujarathi, Satheesh,Hendrickson, Howard P.,Zheng, Guangrong
, p. 3550 - 3553 (2013/07/05)
A highly efficient Amberlite IR-120H resin mediated nucleophilic substitution of the hydroxyl group of propargylic alcohols with a wide range of nucleophiles is reported. The reactions were achieved under very mild conditions in excellent yields.
Iron-catalyzed regioselective hydroaryloxylation of C≡C Triple Bonds: An efficient synthesis of 2H-1-benzopyran derivatives
Xu, Xiaobing,Liu, Jun,Liang, Linfeng,Li, Hongfeng,Li, Yanzhong
supporting information; experimental part, p. 2599 - 2604 (2009/12/31)
An efficient, regioselective, iron-catalyzed intramolecular hydroaryloxylation of 2-propargylphenols or naphthols is reported. The reactions proceed through an endo-dig cyclization to afford benzopyran or naphthopyran derivatives in good to high yields us
