1214896-24-8Relevant articles and documents
Lithium perchlorate-induced electrophilic activation: one-pot synthesis of 3-aryl-2-thioxotetrahydropyrimidin-4-one derivatives from aryl isothiocyanates
Kumar, Varun,Nair, Vipin A.
experimental part, p. 966 - 969 (2010/04/29)
A novel methodology for the synthesis of N-substituted-3-aryl-2-thioxotetrahydropyrimidin-4(1H)-one derivatives had been developed by the condensation of aryl isothiocyanates with β-amino esters using lithium perchlorate as a catalyst and triethylamine as a base. This strategy not only overcomes the disadvantages of the reported methods but also provides high yield of the product in short span of time by an easily workable procedure.
