1214914-47-2

Basic information

• Product Name: C₂₅H₂₇NO
• Synonyms: C₂₅H₂₇NO
• CAS NO: 1214914-47-2
• Molecular Weight: 357.495
• Mol File: 1214914-47-2.mol

Chemical Properties

• CAS DataBase Reference: C₂₅H₂₇NO(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₅H₂₇NO(1214914-47-2)
• EPA Substance Registry System: C₂₅H₂₇NO(1214914-47-2)

Safety Data

• Hazardous Substances Data: 1214914-47-2(Hazardous Substances Data)

Upstream product

• 1214914-45-0 (7aS,11S,13R)-11-(2-propenyl)-13-phenyl-7a,8,10,11-tetrahydro-9H,13H-naphtho[1,2-e]pyrido[2,1-b][1,3]oxazine 

Downstream Products

• 1214914-33-6 1-(methoxybenzyl)naphthalen-2-ol 
• 133294-33-4 (S)-2-allylpiperidine 

Relevant articles and documents

Preparation of enantiopure substituted piperidines containing 2-alkene or 2-alkyne Chains: Application to total syntheses of natural quinolizidine- alkaloids

"Chemical Equation Presented" A general method, for the preparation of enantiopure 2-alkene- or 2-alkyne-containing chain substituted piperidines was established by using nonracemic Betti base as a chiral auxiliary. The key step is that the auxiliary residue was removed by a novel base-catalyzed N-debenzylation via a formation of o-quinone methide mechanism in stead, of the traditional hydrogenolysis, by which the alkene or alkyne groups survived. By this method, ten 2-alkene- or 2-alkyne-containing chain substituted piperidines were prepared on the gram scale within a few hours. To demonstrate the efficiency of the method and the versatility of the product, total, syntheses of natural alkaloids (+)-pelletierine((-)-lasubine II, and (-)-cermizine C were achieved by using (S)-2-allyl-N-Bocpiperidine as a versatile building block.