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(2-Hydroxy-ethyl)-phenyl-carbamic acid tert-butyl ester, with the molecular formula C13H19NO3, is a chemical compound that serves as a reagent in organic synthesis and pharmaceutical research. As a tert-butyl ester derivative of phenylcarbamic acid, its unique structure endows it with versatile applications in the field of chemistry. It is recognized for its role as a building block in the synthesis of organic compounds and is valued for its utility as a protective group for certain functional groups in organic synthesis. Moreover, it exhibits potential pharmacological activity and is under investigation for its role in the development of new drugs.

121492-10-2

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121492-10-2 Usage

Uses

Used in Organic Synthesis:
(2-Hydroxy-ethyl)-phenyl-carbamic acid tert-butyl ester is used as a building block for the synthesis of various organic compounds. Its unique structure allows it to be a key component in the creation of complex organic molecules, contributing to the advancement of chemical research and development.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (2-Hydroxy-ethyl)-phenyl-carbamic acid tert-butyl ester is used as a reagent to aid in the discovery and development of new drugs. Its potential pharmacological activity makes it a candidate for further study and application in medicinal chemistry.
Used as a Protective Group in Organic Synthesis:
(2-Hydroxy-ethyl)-phenyl-carbamic acid tert-butyl ester is utilized as a protective group for certain functional groups during organic synthesis. This role is crucial for preventing unwanted reactions from occurring with these functional groups, thereby ensuring the successful synthesis of the desired compounds.
Used in Drug Development:
(2-Hydroxy-ethyl)-phenyl-carbamic acid tert-butyl ester is being studied for its potential use in the development of new drugs. Its pharmacological properties are of interest to researchers who aim to harness its potential for therapeutic applications, potentially leading to the creation of novel medications for various medical conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 121492-10-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,4,9 and 2 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 121492-10:
(8*1)+(7*2)+(6*1)+(5*4)+(4*9)+(3*2)+(2*1)+(1*0)=92
92 % 10 = 2
So 121492-10-2 is a valid CAS Registry Number.

121492-10-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl N-(2-hydroxyethyl)-N-phenylcarbamate

1.2 Other means of identification

Product number -
Other names Carbamic acid,(2-hydroxyethyl)phenyl-,1,1-dimethylethyl ester (9CI)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:121492-10-2 SDS

121492-10-2Relevant articles and documents

Preparation, characterization and application of 1,4-disulfopiperazine-1,4-diium chloride ([Piper-(SO3H)2]·2Cl) as an efficient dicationic ionic catalyst for the N-Boc protection of amines

Koodehi, Tahereh Ghauri,Shirini, Farhad,Goli-Jolodar, Omid

, p. 443 - 456 (2017/01/10)

In this work, 1,4-disulfopiperazine-1,4-diium chloride ([Piper-(SO3H)2]·2Cl), as a novel Br?nsted acidic ionic catalyst is synthesized and characterized using a series of techniques including FT-IR, TGA, DTA, SEM, pH analysis and Hammett acidity function. This substance can significantly catalyze the N-Boc protection of amines without solvent interference at room temperature. The advantages of this manner are chemoselectivity, short reaction times, suitable yields, excellent yields of the products, without solvent interference and ease of preparation as well as reusability of the catalyst.

Synthetic method of artificial selenium enzyme

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Paragraph 0008; 0009; 0010; 0011; 0012; 0013, (2017/07/20)

The invention discloses a synthetic method of artificial selenium enzyme and relates to a synthetic method of a compound. The synthetic method mainly comprises three steps of synthesis of a double-seleniumcompound with a benzene ring, synthesis of a butan

Silver-Catalyzed Three-Component 1,1-Aminoacylation of Homopropargylamines: α-Additions for Both Terminal Alkynes and Isocyanides

Tong, Shuo,Piemontesi, Cyril,Wang, Qian,Wang, Mei-Xiang,Zhu, Jieping

supporting information, p. 7958 - 7962 (2017/06/27)

The reaction of secondary homopropargylamines, isocyanides, and water in the presence of a catalytic amount of silver acetate and subsequent purification by chromatography on silica gel afforded substituted proline amides in good to excellent yields. Primary homopropargylamines underwent a cyclizative Ugi–Joullié three-component reaction with isocyanides and carboxylic acids to afford functionalized N-acyl proline amides. High diastereoselectivity was observed in the synthesis of 4-alkoxy and 4,5-disubstituted proline derivatives. This work represents the first examples of a three-component cyclizative 1,1-aminoacylation of terminal alkynes.

SELECTIVE HDAC6 INHIBITORS

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Page/Page column 56, (2015/07/15)

The present invention provides hydroxamic acids of the formula described herein, that have activity toward inhibiting histone deacetylases, and in particular HDAC6. Also contemplated are pharmaceutical compositions and methods of use of an effective amount of the hydroxamic acid compounds provided, for treating a disease in a subject. In certain embodiments, the subject is afflicted with cancer, neurodegenerative disease, or HIV infection.

CONTROLLED HNO RELEASE THROUGH INTRAMOLECULAR CYCLIZATION-ELIMINATION

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Page/Page column 42, (2014/05/24)

Protected HNO donors designed to undergo non-enzymatic release at neutral pH via an intramolecular cyclization-elimination are disclosed. The rate of cyclization, and therefore HNO release, can be controlled by substituents and chain length. Thus, biologi

An iron-promoted aldehyde-diene cyclocoupling reaction

Pearson, Anthony J.,Sun, Huikai

, p. 7693 - 7700 (2008/02/13)

(Chemical Equation Presented) A stereospecific intramolecular iron tricarbonyl-promoted aldehyde-diene cyclocoupling reaction was investigated by using simple substrates 6 and more complicated substrates 30a/30b. Demetalation of the initial products conve

A rate enhancement of tert-butoxycarbonylation of aromatic amines with Boc2O in alcoholic solvents

Vilaivan, Tirayut

, p. 6739 - 6742 (2007/10/03)

A rate enhancement of tert-butoxycarbonylation of aromatic amines by Boc2O in alcohols compared to aprotic solvents was demonstrated. Kinetic analysis by NMR suggested that the reaction in CD3OD was faster than in CDCl3 by a factor of 70. Reactions between Boc2O and various aliphatic and aromatic amines in ethanol provided the N-Boc derivatives in good to excellent yields in short reaction times.

Piperidinyl and piperazinyl compounds substituted with bicyclo-heterocyclylalkyl groups useful as CCR3 receptor antagonists

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Page/Page column 14, (2010/02/11)

Compounds having the Formula (I), are useful as CCR3 receptor antagonists, wherein Ar is aryl or heteroaryl; Q is —C(═O)— or C1-2alkylene; X is N(+)R9a, or N; Y is CR9b, or N; R2 is hydrogen or alkyl; R3 and R4 are as defined in the specification; Uc is a mono- or bicyclic group as defined in the specification; n is 0 or 1; and p is 0, 1, 2, 3 or 4.

Pyridinium derivatives, their production and use

-

, (2008/06/13)

Novel pyridinium derivatives represented by the formula (I): STR1 wherein STR2 is an optionally substituted pyridinium ring; R1 is a lower alkyl group or aralkyl group; R7 and R10 are independently hydrogen, a lower alkyl group, aryl group or aralkyl group; l is 0 or 1; R5 is a phenylene group or an alkylene group which may be substituted; R11 is an alkyl group or aryl group; X is a group of the formula: --CH2 OCH2 -- or a group of the formula: STR3 wherein R6 is hydrogen, a lower alkyl or a lower alkoxy, and m is an integer of 0 to 3; U is a group of the formula: STR4 wherein R4 is hydrogen, a lower alkyl group, aryl group or aralkyl group; Y and Z are independently a divalent chain group consisting of one to six members which is selected from the class consisting of groups of the formulae: STR5 wherein R is hydrogen, a lower alkyl group, acyl group or aryl group and at least one of which is a group of the formula: STR6 with the proviso that R may be the same or different from each other, or may form a ring together when two or more groups of the formula: STR7 are present, that R may be bonded to R4 when Y contains a group of the formula: STR8 and that R may be bonded to R11 when Z contains a group of the formula: STR9 and W? is a counter anion; are useful as a platelet activating factor antagonist.

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