1214924-04-5

Basic information

• Product Name: (1R,2S,3R,4R,5R)-3-[(2-chloro-5-fluoropyrimidin-4-yl)amino]-5-({[(3-nitrobenzyl)-sulfonyl]amino}methyl)bicyclo[2.2.1]heptane-2-carboxamide
• Synonyms: (1R,2S,3R,4R,5R)-3-[(2-chloro-5-fluoropyrimidin-4-yl)amino]-5-({[(3-nitrobenzyl)-sulfonyl]amino}methyl)bicyclo[2.2.1]heptane-2-carboxamide
• CAS NO: 1214924-04-5
• Molecular Weight: 512.949
• Mol File: 1214924-04-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S,3R,4R,5R)-3-[(2-chloro-5-fluoropyrimidin-4-yl)amino]-5-({[(3-nitrobenzyl)-sulfonyl]amino}methyl)bicyclo[2.2.1]heptane-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,3R,4R,5R)-3-[(2-chloro-5-fluoropyrimidin-4-yl)amino]-5-({[(3-nitrobenzyl)-sulfonyl]amino}methyl)bicyclo[2.2.1]heptane-2-carboxamide(1214924-04-5)
• EPA Substance Registry System: (1R,2S,3R,4R,5R)-3-[(2-chloro-5-fluoropyrimidin-4-yl)amino]-5-({[(3-nitrobenzyl)-sulfonyl]amino}methyl)bicyclo[2.2.1]heptane-2-carboxamide(1214924-04-5)

Safety Data

• Hazardous Substances Data: 1214924-04-5(Hazardous Substances Data)

Upstream product

• 1214923-81-5 (1S,2S,3R,4R)-3-[(2-chloro-5-fluoropyrimidin-4-yl)amino]-5-cyanobicyclo[2.2.1]heptane-2-carboxamide 
• 871357-93-6 (1S,2S,3R,4R)-3-(2-chloro-5-fluoropyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide 
• 1214923-82-6 (1R,2S,3R,4R,5R)-5-(aminomethyl)-3-[(2-chloro-5-fluoropyrimidin-4-yl)-amino]-bicyclo[2.2.1]heptane-2-carboxamide 
• 58032-84-1 (3-nitrophenyl)methanesulfonyl chloride 

Relevant articles and documents

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Macrocyclic derivative compounds that inhibit protein kinase enzymes are disclosed along with pharmaceutical compositions comprising these compounds and methods for synthesizing the same. Such compounds have utility in the treatment of proliferative diseases resulting from unregulated and/or disturbed kinase activity such as cancers, psoriasis, viral and bacterial infections, inflammatory and autoimmune diseases.