1214989-28-2Relevant articles and documents
A cascade approach to captodative trifluoromethylated enamines or vinylogous guanidinium salts: aromatic substituents as switches of reaction direction
Rulev, Alexander Yu,Muzalevskiy, Vasiliy M.,Kondrashov, Evgeniy V.,Ushakov, Igor A.,Shastin, Aleksey V.,Balenkova, Elizabeth S.,Haufe, Guenter,Nenajdenko, Valentine G.
experimental part, p. 300 - 310 (2010/04/24)
β-Halo-β-(trifluoromethyl)styrenes readily react with a variety of nitrogen nucleophiles bearing primary amino groups to afford either the captodative trifluoromethylated enamines or vinylogous guanidinium salts in a selective fashion depending on the electronic natures of the aromatic substituents.
