1214997-78-0 Usage
General Description
4-Iodo-1-Methyl-1H-pyrazole-3-carbaldehyde is a chemical compound with the molecular formula C7H6IN3O. It is a pyrazole-based aldehyde that contains an iodo substituent at the 4-position and a methyl substituent at the 1-position. 4-Iodo-1-Methyl-1H-pyrazole-3-carbaldehyde is commonly used as a building block in organic synthesis and as a reagent in chemical reactions. Its unique structure and reactivity make it valuable in the production of various pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, it is also used in research and development activities in the field of medicinal chemistry and drug discovery. Overall, 4-Iodo-1-Methyl-1H-pyrazole-3-carbaldehyde is a versatile chemical compound with diverse applications in the chemical and pharmaceutical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1214997-78-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,4,9,9 and 7 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1214997-78:
(9*1)+(8*2)+(7*1)+(6*4)+(5*9)+(4*9)+(3*7)+(2*7)+(1*8)=180
180 % 10 = 0
So 1214997-78-0 is a valid CAS Registry Number.
1214997-78-0Relevant articles and documents
Preparation method of 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester
-
Paragraph 0036; 0040-0042, (2020/06/20)
The invention discloses a preparation method of 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester, and belongs to the technical field of organic synthesis. The preparation method comprises the following steps: with 1,3-dimethylpyrazole as a raw material, carrying out halogenation to obtain 4-halogenated-1,3,5-tetrahydronaphthalene; carrying out a reaction under the conditions of a bromination reagent and AIBN and hydrolysis with hexamethylenetetramine to obtain 4-halogen-1-methyl-1H-pyrazole-3-formaldehyde, then performing a reaction with a fluorination reagent to obtain 4-halogen-3-difluoromethyl-1-methylpyrazole; finally carrying out a reaction on the 4-halogen-3-difluoromethyl-1-methylpyrazole and a Grignard reagent to obtain 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester. The method is simple and convenient to operate and high in reaction yield, the purity of the obtained product can reach 99.5% or above, and the method has a potential process amplification prospect.
