1215003-10-3Relevant academic research and scientific papers
Discovery and optimization of RO-85, a novel drug-like, potent, and selective P2X3 receptor antagonist
Brotherton-Pleiss, Christine E.,Dillon, Michael P.,Ford, Anthony P.D.W.,Gever, Joel R.,Carter, David S.,Gleason, Shelley K.,Lin, Clara J.,Moore, Amy G.,Thompson, Anthony W.,Villa, Marzia,Zhai, Yansheng
scheme or table, p. 1031 - 1036 (2010/06/14)
Despite the extensive literature describing the role of the ATP-gated P2X3 receptors in a variety of physiological processes the potential of antagonists as therapeutic agents has been limited by the lack of drug-like selective molecules. In th
