1215035-97-4Relevant academic research and scientific papers
Remarkable reaction rate and excellent enantioselective direct α-amination of aldehydes with azodicarboxylates catalyzed by pyrrolidinylcamphor-derived organocatalysts
Liu, Pang-Min,Chang, Chihliang,Reddy, Raju Jannapu,Ting, Ying-Fang,Kuan, Hsuan-Hao,Chen, Kwunmin
supporting information; experimental part, p. 42 - 46 (2010/03/24)
Remarkable reaction rate and excellent enantioselective direct α-amination of unmodified aldehydes with various azodicarboxylates was catalyzed by pyrrolidinylcamphor organocatalyst 2a (5 mol-%) to provide the desired aminated products with excellent chemical yields and high to excellent levels of enantioselectivity (up to >99%ee) at 0 °C in CH 2Cl2.
