1215099-07-2

Upstream product

• 1215098-99-9 (S)-[(1R,4R)-4-[(S)-(tert-butyldimethylsilyloxy)((R)-1,4-dioxaspiro[4.5]decan-2-yl)methyl]cyclopent-2-enyl](phenyl)methanol 
• 20445-33-4 (R)-methoxytrifluoromethylphenylacetyl chloride 

Relevant academic research and scientific papers

Desymmetrization of meso-2-alkene-1,4-diol derivatives through copper (I)-catalyzed asymmetric boryl substitution and stereoselective allylation of aldehydes

(Figure prsented) Breaking the mirror: The reaction sequence described in the title was applied to the synthesis of a valuable chiral drug precursor and the rapid stereoselective assembly of complex compounds with multiple chiral centers (see scheme).