121511-91-9

Upstream product

• 24522-26-7 N-(4-bromophenyl)-2-cyanoacetamide 

Downstream Products

• 1447585-57-0 N-(4-bromophenyl)-2-{2-[(4-bromophenyl)amino]-2-oxoethyl}-6-thioxo-1,6-dihydropyrimidine-5-carboxamide 
• 1447585-69-4 4-[(2-anilino-2-oxoethyl)thio]-N-(4-bromophenyl)-2-{2-[(4-bromophenyl)amino]-2-oxoethyl}pyrimidine-5-carboxamide 
• 1447585-70-7 4-{[2-(benzylamino)-2-oxoethyl]thio}-N-(4-bromophenyl)-2-{2-[(4-bromophenyl)amino]-2-oxoethyl}pyrimidine-5-carboxamide 
• 1447585-71-8 N-(4-bromophenyl)-2-{2-[(4-bromophenyl)amino]-2-oxoethyl}-4-({2-[(2-methylphenyl)amino]-2-oxoethyl}thio)pyrimidine-5-carboxamide 
• 1447585-72-9 N-(4-bromophenyl)-2-{2-[(4-bromophenyl)amino]-2-oxoethyl}-4-({2-[(4-methylphenyl)amino]-2-oxoethyl}thio)pyrimidine-5-carboxamide 
• 1447585-73-0 N-(4-bromophenyl)-2-{2-[(4-bromophenyl)amino]-2-oxoethyl}-4-({2-[(2-ethylphenyl)amino]-2-oxoethyl}thio)pyrimidine-5-carboxamide 
• 1447585-74-1 N-(4-bromophenyl)-2-{2-[(4-bromophenyl)amino]-2-oxoethyl}-4-({2-[(4-ethylphenyl)amino]-2-oxoethyl}thio)pyrimidine-5-carboxamide 
• 1447585-75-2 N-(4-bromophenyl)-2-{2-[(4-bromophenyl)amino]-2-oxoethyl}-4-({2-[(2,6-dimethylphenyl)amino]-2-oxoethyl}thio)pyrimidine-5-carboxamide 
• 1447585-76-3 N-(4-bromophenyl)-2-{2-[(4-bromophenyl)amino]-2-oxoethyl}-4-({2-[(2,4-dimethylphenyl)amino]-2-oxoethyl}thio)pyrimidine-5-carboxamide 
• 1447585-77-4 N-(4-bromophenyl)-2-{2-[(4-bromophenyl)amino]-2-oxoethyl}-4-({2-[(3-chloro-2-methylphenyl)amino]-2-oxoethyl}thio)pyrimidine-5-carboxamide 
• 1447585-78-5 N-(4-bromophenyl)-2-{2-[(4-bromophenyl)amino]-2-oxoethyl}-4-{[2-(4-methylphenyl)-2-oxoethyl]thio}pyrimidine-5-carboxamide 
• 1447585-79-6 N-(4-bromophenyl)-2-{2-[(4-bromophenyl)amino]-2-oxoethyl}-4-{[2-(4-chlorophenyl)-2-oxoethyl]thio}pyrimidine-5-carboxamide 
• 121511-95-3 5-p-bromophenylamino-4-thiocarbamoyl-1,2,3-thiadiazole 
• 121512-00-3 5-amino-4-N-p-bromophenylthiocarbamoyl-1,2,3-thiadiazole 

Relevant academic research and scientific papers

Unexpected result in the reaction of 3-amino-3-thioxopropanamides with 2-anilinomethylene derivatives of 1,3-dicarbonyl compounds. synthesis of pyrimidine-5-carboxamide derivatives

The interaction of 3-amino-3-thioxopropanamides with 2-anilinomethylene derivatives of dimedone, 1,3-cyclohexanedione and Meldrum's acid led to the formation of 2-(2-amino-2-oxoethyl)-6-thioxo-1,6-dihydropyrimidine-5- carboxamides. The latter were alkylated in alkaline medium with the formation of 4-(alkylthio)pyrimidine-5-carboxamide derivatives.