1215112-71-2

Upstream product

• 110-91-8 morpholine 
• 99-61-6 3-nitro-benzaldehyde 
• 536-74-3 phenylacetylene 

Relevant academic research and scientific papers

Green bio-based synthesis of Fe2O3@SiO2-IL/Ag hollow spheres and their catalytic utility for ultrasonic-assisted synthesis of propargylamines and benzo[b]furans

A novel magnetic hybrid system containing nano-magnetic Fe2O3 hollow spheres, silica shell, [pmim]Cl ionic liquid and silver nanoparticles was synthesized and characterized. The silver nanoparticles were prepared via biosynthesis usi

Biradicalo-iminobenzosemiquinonato(1?) complexes of nickel(ii): catalytic activity in three-component coupling of aldehydes, amines and alkynes

The six-coordinated bis-o-iminosemiquinone complex,NiL2BIS, in whichLBISis theo-iminosemiquinone 1-electron oxidized form of the tridentateo-aminophenol benzoxazole-based ligandH2LBAP, was synthesized

Copper-based catalysts derived from salen-type ligands: Synthesis of 5-substituted-1: H-tetrazoles via [3+2] cycloaddition and propargylamines via A3-coupling reactions

Base-metal copper(ii) complexes derived from unsymmetrical salen-type ligands were designed and synthesized using ligands L1H to L4H in moderate yield. The synthesized unsymmetrical ligands L1H to L4H and the corresponding copper complexes (1-4) were characterized by UV-visible, IR and ESI-MS spectroscopic studies. Molecular structures of complexes 1, 2 and 4 were determined by X-ray crystallography. Copper complexes 1-4 were employed as catalysts for [3+2] cycloaddition and A3-coupling reactions. The mutual approach of salen-type ligands and metals via active participation of ligands allow to achieve the catalytic reactions. Reaction pathways were proposed and possible intermediate species during the catalytic cycle were successfully characterized by ESI-MS spectroscopic studies. This journal is

One-pot three-component synthesis of propargylamines using an efficient and reusable copper bio-functionalized magnetic graphene oxide nanocomposite

In this work, magnetic graphene oxide was produced through chemical oxidation of the graphite powder, exfoliation under ultrasonic waves and then magnetization in the presence of ion salts. Magnetic graphene oxide was functionalized with cysteine and used

Solvent-free synthesis of propargylamines catalyzed by an efficient recyclable ZnO-supported CuO/Al2O3 nanocatalyst

An efficient nanocatalyst of ZnO-supported CuO/Al2O3 (CuO/ZnO/Al2O3 nanocatalyst) was prepared by the co-precipitation method and characterized by scanning electron microscopy, energy-dispersive X-ray spectrosco

CuI@Sulfur-functionalized halloysite nanoclay: a novel recyclable catalyst for the ultrasonic-assisted synthesis of propargylamines: a combination of experimental and DFT simulation

A novel heterogeneous catalyst, CuI supported on sulfur functionalized halloysite (CuI@HNTs-S), was designed and synthesized through functionalization of the halloysite nanoclay surface with 3-mercaptopropyl trimethoxysilane and subsequent immobilization of CuI. The catalyst was characterized by using various characterization techniques such as FTIR, SEM/EDS, XRD, ICP and TGA. The catalytic activity of CuI@HNTs-S for the synthesis of propargylamines through ultrasonic-assisted multi-component A3 coupling reaction of aldehydes, phenyl acetylene and amines was also studied. The results established that CuI@HNTs-S could efficiently catalyze the reaction to furnish the desired products in excellent yield and in short reaction time. Notably the catalyst was recyclable and could be recycled with slight loss of the catalytic activity for five reaction runs. Then, the ability of pristine HNTs and sulfur functionalized HNTs toward CuI grabbing was compared quantitatively using molecular simulation. Calculated energies confirmed better performance of HNTs-S toward CuI physisorption, which decreases its leaching during catalytic reaction. This result was experimentally confirmed by observing the superior recyclability and low copper leaching of CuI@HNTs-S compared to CuI@HNTs.

Ultrasonic and bio-assisted synthesis of Ag@HNTs-T as a novel heterogeneous catalyst for the green synthesis of propargylamines: A combination of experimental and computational study

A novel heterogeneous catalyst is prepared through functionalization of halloysite nanotube with 1H-1,2,3-triazole-5-methanol and subsequent immobilization of silver nanoparticles through bio-assisted approach using Arctiumplatylepis extract. The resulting catalyst, Ag@HNTs-T, was characterized by using SEM/EDX, BET, XRD, FTIR, ICP-AES, TGA, DTGA and elemental mapping analysis. Moreover, we computationally assessed metal-ligand interactions in Ag@HNTs-T complex model to interpret the immobilization behavior of silver nanoparticles on HNTs surface via quantum chemistry computations. The catalytic activity of the catalyst was studied for the synthesis of propargylamines via A3 and KA2 coupling reactions under ultrasonic irradiation. The results demonstrated that Ag@HNTs-T could efficiently promote these reactions to furnish the corresponding products in high yields and short reaction times. The study of the recyclability of the catalyst and Ag(0) leaching confirmed that the catalyst was recyclability up to four reaction runs with slight Ag(0) leaching.

Metal- and catalyst-free, one-pot, three-component synthesis of propargylamines in magnetized water: Experimental aspects and molecular dynamics simulation

Magnetized water (MW), as a green-promoting medium, is applied for the one-pot, metal- and catalyst-free, practical, efficient, and environmentally benign three-component reactions of aldehydes, amines, and alkynes. The salient features of this novel meth

Chitosan-supported copper as an efficient and recyclable heterogeneous catalyst for A3/decarboxylative A3-coupling reaction

Chitosan-supported copper (chit@copper) based heterogeneous catalysts have been explored for A3-coupling and decarboxylative A3-coupling. The developed protocol employs low catalyst loading, solventless condition and easy work-up for

Copper(II) chelate-bonded magnetite nanoparticles: A new magnetically retrievable catalyst for the synthesis of propargylamines

In this study, we document the use of a reusable magnetic nanoparticle (MNP)-supported copper catalyst for the efficient synthesis of propargylamines via the A3 coupling of benzaldehydes, phenylacetylene, and piperidine or morpholine. The new MNPs were characterized by scanning electron microscopy, energy dispersive X-ray analysis, Fourier transform infrared spectroscopy, thermogravimetric analysis, and vibrating sample magnetometry. Notably, the activity and leaching test of the catalyst indicated that the MNPs could be reused without loss to its catalytic activity or leaching of its copper ligands.