1215119-06-4Relevant articles and documents
Design and synthesis of new tricyclic indoles as potent modulators of the S1P1 receptor
Buzard, Daniel J.,Schrader, Thomas O.,Zhu, Xiuwen,Lehmann, Juerg,Johnson, Ben,Kasem, Michelle,Kim, Sun Hee,Kawasaki, Andrew,Lopez, Luis,Moody, Jeanne,Han, Sangdon,Gao, Yinghong,Edwards, Jeff,Barden, Jeremy,Thatte, Jayant,Gatlin, Joel,Jones, Robert M.
, p. 659 - 663 (2015/01/30)
Modulators of S1P1 have proven utility for the treatment of autoimmune disease and efforts to identify new agents with improved safety and pharmacokinetic parameters are ongoing. Several new S1P1 chemotypes were designed and optimize