1215172-32-9

Basic information

• Product Name: (S)-1-((R)-2-amino-4-methylpentanoyl)-N-(3-chlorobenzyl)pyrrolidine-2-carboxamide hydrochloride
• Synonyms: (S)-1-((R)-2-amino-4-methylpentanoyl)-N-(3-chlorobenzyl)pyrrolidine-2-carboxamide hydrochloride
• CAS NO: 1215172-32-9
• Molecular Weight: 388.337
• Mol File: 1215172-32-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-1-((R)-2-amino-4-methylpentanoyl)-N-(3-chlorobenzyl)pyrrolidine-2-carboxamide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-((R)-2-amino-4-methylpentanoyl)-N-(3-chlorobenzyl)pyrrolidine-2-carboxamide hydrochloride(1215172-32-9)
• EPA Substance Registry System: (S)-1-((R)-2-amino-4-methylpentanoyl)-N-(3-chlorobenzyl)pyrrolidine-2-carboxamide hydrochloride(1215172-32-9)

Safety Data

• Hazardous Substances Data: 1215172-32-9(Hazardous Substances Data)

Upstream product

• 1189747-62-3 (S)-tert-butyl 2-((3-chlorobenzyl)carbamoyl)pyrrolidine-1-carboxylate 
• 4152-90-3 m-chlorobenzylamine 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 16937-99-8 N-Boc-D-Leu 
• 1189747-64-5 (S)-N-(3-chlorobenzyl)pyrrolidine-2-carboxamide hydrochloride 
• 116662-96-5 (2R)-2-(1,1-dimethylethoxycarbonylamino)-4-methylpentanal 
• 129603-01-6 (R)-N^α-(tert-butoxycarbonyl)-N-methoxy-N-methylleucinamide 
• 1215172-22-7 tert-butyl (R)-1-((S)-2-(3-chlorobenzylcarbamoyl)pyrrolidin-1-yl)-4-methyl-1-oxopentan-2-ylcarbamate 

Relevant articles and documents

Binding cooperativity between a ligand carbonyl group and a hydrophobic side chain can be enhanced by additional H-bonds in a distance dependent manner: A case study with thrombin inhibitors

One of the underappreciated non-covalent binding factors, which can significantly affect ligand-protein binding affinity, is the cooperativity between ligand functional groups. Using four different series of thrombin inhibitors, we reveal a strong positiv