1215180-93-0Relevant articles and documents
Copper-catalyzed γ-selective and stereospecific direct allylic alkylation of terminal alkynes: Synthesis of skipped enynes
Makida, Yusuke,Takayama, Yurie,Ohmiya, Hirohisa,Sawamura, Masaya
supporting information, p. 5350 - 5354 (2013/06/05)
Skipping out: The title reaction using internal secondary allylic phosphates proceeded with excellent γ regioselectivity and E stereoselectivity to give skipped enynes. Enantioenriched secondary allylic phosphates proceeded with 1,3-anti stereochemistry t
Copper-catalyzed γ-selective and stereospecific allylic alkylation of ketene silyl acetals
Li, Dong,Ohmiya, Hirohisa,Sawamura, Masaya
, p. 5672 - 5675 (2011/06/18)
Copper-catalyzed allylic alkylation of ketene silyl acetals proceeded with excellent γ-E-selectivity. Efficient α-to-γ chirality transfer with anti-selectivity occurred in the reaction of enantioenriched secondary allylic phosphates, affording enantioenri
Copper-catalyzed γ-selective and stereospecific allyl-aryl coupling between (Z)-acyclic and cyclic allylic phosphates and arylboronates
Ohmiya, Hirohisa,Yokokawa, Natsumi,Sawamura, Masaya
supporting information; experimental part, p. 2438 - 2440 (2010/07/10)
A Cu-catalyzed allyl-aryl coupling reaction between (Z)-acyclic or cyclic allylic phosphates and arylboronates proceeds with excellent γ-E-selectivity and 1,3-anti chirality transfer, which gives the corresponding coupling products with benzylic and allylic stereogenic centers. The wide availability and easy-to-handle nature of arylboronates, the inexpensiveness of the Cu catalyst system, and the high regio- and stereoselectivities are attractive features of this protocol.