1215288-70-2Relevant academic research and scientific papers
K3PO4-catalyzed regiospecific aminobromination of βnitrostyrene derivatives with N-Bromoacetamide as aminobtominating agent
Chen, Zhan-Guo,Wang, Yun,Wei, Jun-Fa,Zhao, Peng-Fei,Shi, Xian-Ying
supporting information; experimental part, p. 2085 - 2088 (2010/06/16)
"Chemical Equation Presented" A very simple, efficient, and regiospecific protocol for aminobromination of a wide scope of β-nitrostyrene derivatives with N-bromoacetamide (NBA) as nitrogen/ bromine sources has been developed by using K3PO4 as catalyst. The reaction proceeded smoothly and cleanly to give the bromoamines in good to excellent yields (78-99%) within 24 h in CH2Cl2 at room temperature without protection of inert gases. A possible mechanism involving a nucleophilic conjugate addition was proposed.
