1215664-29-1Relevant academic research and scientific papers
Highly diastereoselective pd-catalyzed carboetherification reactions of acyclic internal alkenes. Stereoselective synthesis of polysubstituted tetrahydrofurans
Ward, Amanda F.,Wolfe, John P.
supporting information; experimental part, p. 1268 - 1271 (2010/05/18)
Chemical Equation Presented A highly diastereoselective synthesis of substituted tetrahydrofurans bearing stereocenters at C2 and C1′ via Pd-catalyzed carboetherification reactions of acyclic internal alkenes is described. Use of an improved catalyst composed of Pd 2(dba)3/S-Phos provides products with up to >20;1 dr. The stereoselective preparation of tetrahydrofurans containing three stereocenters, including a molecule structurally related to simplakidine A, is also reported.
