121573-02-2Relevant academic research and scientific papers
Inhibition of lipid peroxidation mediated by indolizines
Nasir, Achmad Izuddin,Gundersen, Lise-Lotte,Rise, Frode,Antonsen, yvind,Kristensen, Trond,Langhelle, Bjarte,Bast, Aalt,Custers, Ilse,Haenen, Guido R. M. M.,Wikstroem, Hakan
, p. 1829 - 1832 (1998)
Esters, ethers, carbonates and carbamates of 1-indolizinols and azaindolizinols exhibit a profound inhibition of lipid peroxidation in vitro. The antioxidants were prepared by cyclization of pyridines and diazines with diphenylcyclopropenone followed by introduction of the O-substituent.
Indolizine 1-sulfonates as potent inhibitors of 15-lipoxygenase from soybeans
Teklu, Solomon,Gundersen, Lise-Lotte,Larsen, Tove,Malterud, Karl E.,Rise, Frode
, p. 3127 - 3139 (2007/10/03)
A number of indolizine 1-sulfonates have been prepared by cyclization of cyclopropenones with pyridines followed by trapping of the intermediate 1-indolizinol with a sulfonyl halide, and examined as inhibitors of 15-lipoxygenase (15-LO). The compounds dis
Indolizines. 2. Preparation of 1- and 3-Indolizinols and Their Esters
Wadsworth, Donald H.,Bender, Steven L.,Smith, Douglas L.,Luss, Henry R.,Weidner, Charles H.
, p. 4639 - 4644 (2007/10/02)
2,3-Diarylcyclopropenones react smoothly with pyridine and substituted pyridines in a variety of solvents to produce 1- and/or 3-indolizinols.The regioisomeric indolizines were characterized by X-ray crystallography of their acetate derivatives.The synthesis and spectroscopic properties of a number of indolizinols and their ester derivatives are described.
