121671-82-7Relevant academic research and scientific papers
A mild and efficient cleavage of tert-butyldimethylsilyl (TBS) and tetrahydropyranyl (THP) ethers using a catalytic amount of TBPA+ {radical dot} Sb Cl6-
Xu, Yanfen,Tang, Shouchu,Han, Junjie,She, Xuegong,Pan, Xinfu
, p. 3634 - 3637 (2008)
A mild and efficient method for the deprotection of the TBS and THP ethers is described. A wide variety of TBS ethers as well as THP ethers can be easily deprotected to the corresponding parent hydroxyl compounds by employing a catalytic amount of tris(4-bromophenyl)aminium hexachloroantimonate (TBPA+ {radical dot} Sb Cl6-) in methanol at room temperature in good yield.
The "Aqueous" Prins Reaction
Aubele, Danielle L.,Lee, Christopher A.,Floreancig, Paul E.
, p. 4521 - 4523 (2007/10/03)
(Equation presented) In this communication we demonstrate that Prins cyclization reactions occur under very mild conditions when cyclic α,β-unsaturated acetals are employed as oxocarbenium ion progenitors and allylsilanes are used as nucleophiles. Cycliza
Deprotection of acetals and silyl ethers using a polymer-supported π- acid catalyst: Chemoselectivity and polymer effect
Tanaka, Nobuyuki,Masaki, Yukio
, p. 1960 - 1962 (2007/10/03)
A polymeric dicyanoketene acetal (DCKA), prepared from a styrene monomer bearing dicyanoketene acetal functionality, was found to be an effective and recyclable catalyst in the chemoselective deprotection of acetals and silyl ethers. A remarkable acceleration accountable for the polymer effect was observed.
SELECTIVE DE-PROTECTION OF SILYL ETHERS
Prakash, Chandra,Saleh, Samir,Blair, Ian A.
, p. 19 - 22 (2007/10/02)
Pyridinium p-toluenesulfonate has been found to remove t-butyldimethylsilyl ethers selectively in the presence of t-butyldiphenylsilyl ethers.This methodology should find wide applicability in complex organic synthesis.
